[Microcirculatory changes in trauma].

The coherence of macrocirculation, microcirculation, and tissue metabolic response during nontraumatic hemorrhagic shock in swine

Hemorrhagic shock is clinically observed as changes in macrocirculatory indices, while its main pathological constituent is cellular asphyxia due to microcirculatory alterations. The coherence between macro- and microcirculatory changes in different shock states has been questioned. This also applies to the hemorrhagic shock. Most studies, as well as clinical situations, of hemorrhagic shock in...

Microcirculatory Effects of Emulsified Fat Infusions.

• The effects of experimental and clinical hyperlipemia on microcirculation have been considered in discussions and hypotheses regarding the causation of fat embolism, the changes of blood lipids after trauma, and the pathophysiological responses to orally or parenterally administered fat emulsions. The mechanism by which fat embolism develops after traumata, especially fractures, has not been ...

Early Changes in Glutamate Metabolism and Perfusion in Basal Ganglia following Hypoxia-Ischemia in Neonatal Piglets: A Multi-Sequence 3.0T MR Study

The excitotoxicity of glutamate metabolism as well as hemodynamic disorders of the brain are both risk factors for neonatal hypoxic-ischemic brain damage (HIBD). In the present study, changes in glutamate metabolism in the basal ganglia were detected by proton magnetic resonance spectroscopy (1H-MRS) at 0-6, 8-12, 24-30, and 48-60 h after the induction of hypoxia-ischemia (HI) in newborn piglet...

New model for long-term investigations of cutaneous microcirculatory and inflammatory changes following irradiation

Radiotherapy is used for curative and palliative treatment. However, its negative effect on normal tissue is a limiting factor for the deliverable dose. Microcirculatory breakdown and prolonged inflammation in particular are major features of late side effects. The purpose of this study was to develop a reliable animal model that will allow a long-term in vivo analysis of microcirculation and i...

Microcirculatory and biochemical studies of skeletal muscle tissue after high energy missile trauma.